Clinical Evidence & Patents
The inventions of Dr. Muhammed Aslam Nasir are among the most rigorously investigated supraglottic technologies in medical history, validated by multi-center trials in JAMA, endorsed by European & American resuscitation councils, and protected across multinational patent registries.
The Macewen Medal
Named in honor of Sir William Macewen (1848–1924), the Scottish surgeon who performed the world’s first recorded tracheal intubation for anaesthesia in 1878, the Macewen Medal is awarded by the Difficult Airway Society (DAS, UK) to individuals who have made extraordinary, lasting contributions to airway clinical practice.
"Conferred for pioneering the non-inflatable supraglottic seal concept and inventing the i-gel®, transforming routine clinical anaesthesia and emergency resuscitation protocols across hospitals and paramedical services worldwide."
Dr. Muhammed Aslam Nasir Patent Architecture
The foundational engineering disclosures protecting the non-inflatable anatomical perilaryngeal airway seal.
Nasir Laryngeal Airway (NLA / i-gel®)
Landmark Clinical Trials & Guidelines
Over 200+ independent studies validate the safety, seal pressure, and rapid insertion of Dr. Nasir’s airway architectures.
Effect of a Strategy of a Supraglottic Airway Device vs Tracheal Intubation During Out-of-Hospital Cardiac Arrest (AIRWAYS-2 Trial)
Authors: Benger JR, Kirby K, Black S, et al.
A landmark multicenter cluster-randomized clinical trial involving 9,296 adult patients with non-traumatic out-of-hospital cardiac arrest attended by 1,523 paramedics from four ambulance services in England.
Difficult Airway Society 2015 Guidelines for Management of Unanticipated Difficult Intubation in Adults
Authors: Frerk C, Mitchell VS, McNarry AF, et al.
The definitive guidelines for unanticipated difficult intubation in general anaesthesia. Specifies 2nd generation supraglottic airway devices with gastric channels as Plan B rescue devices.
Size 4 i-gel Airway Insertion During Chest Compressions in a Manikin Simulation
Authors: Gatward JJ, Thomas MJ, Nolan JP, Cook TM.
Investigated the feasibility and speed of inserting an i-gel airway during continuous uninterrupted external cardiac compressions.
Evaluation of a New Supraglottic Airway Device in Anaesthetised Feline Patients
Authors: Crotaz I, et al.
Prospective veterinary clinical trial assessing ease of placement, seal quality, and safety of the feline v-gel® supraglottic device compared to traditional cuffed endotracheal tubes.
Clinical Safety and Hemodynamic Stability of v-gel in Pet Rabbits Undergoing Routine Surgery
Authors: Prasse L, Selleri P, et al.
Assessed the veterinary challenge of rabbit airway management, where traditional blind endotracheal intubation results in severe glottic edema and mortality rates of over 1.3%.
Evaluation of the v-gel Advanced Supraglottic Airway Device in Cats Undergoing Controlled Positive-Pressure Ventilation
Authors: Barletta M, Kleine SA, et al.
Multi-parameter evaluation of the next-generation v-gel® advanced device under controlled mechanical ventilation and capnographic monitoring.
Global Patent Portfolio
TALRIA LIMITED DMCC holds and manages foundational patents covering non-inflatable anatomical airway geometry, dual-lumen suction systems, and species-matched veterinary seals.
Laryngeal Airway Device
Pioneering patent covering an anatomical airway device comprising a flexible non-inflatable cuff configured to closely match the contours of the perilaryngeal tissues and epiglottic valleculae, avoiding mucosal ischemia.
Airway Device with Integrated Gastric Channel and Bite Block
Covers second-generation airway device innovations featuring an integral dorsal esophageal conduit enabling gastric aspiration and venting, integrated with buccal stabilization structures.
Nasir Laryngeal Airway Device and Supraglottic Sealing Mechanism
European foundational patent covering the geometry and thermoplastic elastomeric properties providing physiological seal pressures without cuff pressure monitoring.
Species-Specific Veterinary Supraglottic Airway Device
Protects anatomical 3D pharyngolaryngeal bowl configurations specific to feline, lagomorph, and canine airway structures, preventing tracheal ring injury.
Advanced Anatomical Airway with Dual-Lumen Telemetric Monitoring
Next-generation supraglottic device incorporating sensor conduits, integrated capnography sample ports, and reinforced epiglottic barrier structures.
Intellectual Property & Licensing Inquiries
For technology transfer agreements, patent licensing, or regional manufacturing rights, please contact our legal and business development team.